Diuretic and antinatriuretic responses produced by the endogenou

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 2, 530326, A61K 3800, A61K 3810, C07K 700

Patent

active

058406964

ABSTRACT:
Nociceptin in a method of controlling water retention in a patient. More particularly, the use and administration of nociceptin as a free-water diuretic that produces a free-water diuresis for the control of water retention in patients.

REFERENCES:
Meunier, J.C. et al., Nature, 377, 532, Feb. 1995.
Reinscheid, R.K. et al, Science, 270, 792, Mar. 1995.
Giuliani, S. et al. British J. Pharmacol., 118 (7) 1567, Jul. 1996.
Kapusta D. et al. Life Sci. 60 (1) PL15-PL21 Jan. 1997.

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