Diurea derivatives useful as medicaments and processes for the p

Details Diurea derivatives useful as medicaments and processes for the p Diurea derivatives useful as medicaments and processes for the p

1991-09-24

1992-11-24

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564 27, 564 29, 564 50, 564 52, 564 53, 564 54, 564 55, 564 56, 564 57, 564 59, 546309, C07C33514, C07C33508

Patent

active

051664291

ABSTRACT:
Diurea Derivatives represented by the following general formula and salts thereof: ##STR1## The above compounds inhibit acyl-coenzyme A chloresterol acyl-transferase (ACAT enzyme), and thereby control the accumulation of cholesterol ester to the smooth muscle of arterial wall in the blood vessel.

REFERENCES:
patent: 4216228 (1980-08-01), Yamada et al.
patent: 4387105 (1983-06-01), DeVries et al.
Ito et al., CA 165575u, vol. 77, 1972 (abstract corresponding to J 4717899 above).

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