Dithioketal derivatives of 13-polycarbonalkylgon-4-en-3-ones

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07J 3300

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040050785

ABSTRACT:
Novel 3-thioketals of 13-polycarbonalkyl-17-ethynyl-17-hydroxygon-4-ene and 13-polycarbonalkyl-17-chlorethynyl-17-hydroxygon-4-ene, with improved separation of activities, i.e. maximizing progestational and minimizing androgenic action, are prepared from the corresponding 3-carbonyl compounds by treatment with dithioethylene ketal in the presence of an acid catalyst.

REFERENCES:
patent: 3850911 (1974-11-01), Hughes et al.

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