Dithio prostaglandin derivatives

Details Dithio prostaglandin derivatives Dithio prostaglandin derivatives

1977-02-04

1978-08-29

Jaisle, Cecilla M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603436, 260456R, 260468D, 260514D, 424277, 424305, 424311, 560106, 560231, 26034622, C07D33904

Patent

active

041103416

ABSTRACT:
Prostaglandin analogues of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## X represents ethylene or cis-vinylene, Y represents ethylene or trans-vinylene, R.sup.1 represents a straight- or branched-chain alkyl group containing from 4 to 10 carbon atoms, and R.sup.2 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms and cyclodextrin clathrates of such acids and esters and, when R.sup.2 represents a hydrogen atom, non-toxic salts thereof, the bonds attaching the epidithio radical to the carbon atoms in the 9- and 11-positions in the grouping of formula VA being either botn in .alpha.-configuration or both in .beta.-configuration are disclosed.
These compounds exhibit characteristic prostaglandin properties.

REFERENCES:
patent: 3514383 (1970-05-01), Beal et al.
patent: 3845042 (1974-10-01), Strike et al.
patent: 3931296 (1976-01-01), Hayashi et al.
patent: 3950363 (1976-04-01), Bundy
Corey et al., Tetrahedron Letters, #10, pp. 737-740, 1976.

Affiliated with

Also associated with

Rating

Dithio prostaglandin derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dithio prostaglandin derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dithio prostaglandin derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1632699