Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-12-24
2010-06-29
Andres, Janet L (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S473000
Reexamination Certificate
active
07745647
ABSTRACT:
The present invention relates to novel diterpene compounds isolated from the fruiting body ofAntrodia camphorata, especially to the new compounds of following structural formula:and pharmaceutically acceptable salt, solvate, hydrate or biologically active equivalent thereof. The present invention also relates to a pharmaceutical composition containing at least one of the novel diterpene compounds, and a use of the diterpene compound as a neuroprotective agent.
REFERENCES:
patent: 7601854 (2009-10-01), Lai et al.
Chen et al. Journal of Natural Products (2006), 69(4), 689-691.
CC Chen, et al. “Neuroprotective diterpenes from the fruiting body ofAntrodia camphorata”, J. Nat Prod, Apr. 2006, vol. 69, No. 4, Abstract, http://www.ncbi.nlm.nih.gov.
Clardy, John, Using genomics to deliver natural products from symbiotic bacteria, Genome Biology, 2005, 6:232.
Pal et al., Chemical Transformation of Andrographolide, Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2002, 41B(9), 1915-1918 Abstract.
Kuo Yueh-Hsiung
Lai Min-Nan
Shiao Young-Ji
Andres Janet L
Bacon & Thomas PLLC
Chandrakumar Nizal S
Kang Jian Biotech Corp, Ltd.
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