Chemistry: analytical and immunological testing – Optical result – With claimed manipulation of container to effect reaction or...
Patent
1986-12-11
1987-07-21
Richman, Barry S.
Chemistry: analytical and immunological testing
Optical result
With claimed manipulation of container to effect reaction or...
7386323, 73866, 422 68, 422270, 422277, B01D 1102, G01N 100, G01N 3315, G01N 3700
Patent
active
046818588
ABSTRACT:
The invention provides a dissolution cell and method for determining the in-vitro release rate of a drug in suitable form, e.g. a suppository. The cell includes a solid rectangular top wall and a pair of trapezoidal side walls extending from the top wall. Disposed between the side walls are a pair of end walls and a bottom wall each comprised of a wire mesh material. The bottom wall and end walls can be made in one piece. The top wall has an opening and a flanged extension which can be coupled to a suitable rotating device. In use the cell containing the drug is rotated in a suitable dissolution medium and the rate of release of the drug is determined by analyzing the amount of drug released to the dissolution medium at predetermined intervals.
REFERENCES:
patent: 3595623 (1971-07-01), Sperti
patent: 3802272 (1974-04-01), Bischoff et al.
patent: 4108602 (1978-08-01), Hanson et al.
patent: 4279860 (1981-07-01), Smolen
Garrett et al., J. Pharm. Sci., V. 57, No. 6, 1968, pp. 944-948.
Chaudhari Atma
Lee Joseph K. S.
Delahunty C. M.
Nath Gary M.
Richman Barry S.
Warner-Lambert & Company
LandOfFree
Dissolution cell and method for determining the in-vitro release does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dissolution cell and method for determining the in-vitro release, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dissolution cell and method for determining the in-vitro release will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-207342