Dissociative fluorescence enhancement assay

Details Dissociative fluorescence enhancement assay Dissociative fluorescence enhancement assay

2007-05-01

2007-05-01

Warden, Jill (Department: 1743)

Chemistry: analytical and immunological testing

Optical result

With fluorescence or luminescence

C436S536000, C436S537000, C436S546000, C436S082000, C436S086000

Reexamination Certificate

active

10093034

ABSTRACT:
The invention relates to an enhancement solution for an assay technology using lanthanide ions or their chelates as labels and dissociative fluorescence enhancement as a tool for detection, wherein said enhancement solution comprises a β-diketone of formula Iwherein R1is an aryl, optionally mono- or multi-substituted, and R2is a straight or branched alkyl chain with 2 to 9 carbon atoms substituted with four or more fluorine atoms. The invention further relates to a bioaffinity assay using lanthanide ions or their chelates as labels and dissociative fluorescence enhancement as a tool for detection comprising the use of said enhancement solution.

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