Disposable unit in diagnostic assays

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 71, 435 72, 435 792, 435 793, 435 794, 435 795, 436501, 436518, 436519, 436537, 422 55, 422 58, 422 63, C12Q 100, G01N 3353, G01N 33566, G01N 33543

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active

053994868

ABSTRACT:
A disposable diagnostic unit is provided which employs a housing which provides for a sample port, and a channel which feeds the sample to an incubation area by means of capillary action. The incubation area is underneath an optically-clear window and comprises a lipid membrane which has optical properties, particularly fluorescent properties and usually a reagent. A reservoir at the end of the channel downstream from the incubation area receives the sample and waste washes, while on one side of the platform area is a reagent reservoir and on the other side a side waste reservoir, so that one can move the reagent from the reagent reservoir through the platform area into the waste reservoir. Various reagents may be contained within the unit and the necessary liquids added automatically by appropriate instrumentation, so as to have the assay carried out automatically, without technician involvement, providing an accurate and sensitive determination.

REFERENCES:
patent: 5051237 (1991-09-01), Grenner et al.
patent: 5053197 (1991-10-01), Bowen
patent: 5096836 (1992-03-01), Macho et al.
patent: 5156810 (1992-10-01), Ribi
patent: 5164598 (1992-11-01), Hillman et al.

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