Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Patent
1996-03-14
1998-06-16
Jones, W. Gary
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
424486, 424487, 424501, 5147723, 5147726, 5147724, 524100, 524102, 524103, 935 88, 536 253, 435 911, 222478, 222485, 222325, G01N 1506, C07N 2104, A61K 914, C12P 1934
Patent
active
057665508
ABSTRACT:
A disposable cartridge for storage and delivery of reagents for synthesizing and labeling of synthetic oligonucleotides comprises an annular casing, an enclosed area defined by the interior surface of the casing and a non-swellable matrix which is inert to organic solvents is positioned within the enclosed area. Adsorbed onto the surface of the matrix is a reagent to be coupled to an immobilized oligonucleotide precursor. The cartridges can be packaged in such a way as to insure the long-term stability of the reagents contained therein. The cartridge is readily insertable into the reagent delivery line of an automated synthesizer of oligonucleotides and also is useful for the production of labeled oligonucleotides by manual coupling. The cartridges of the invention are disposable after a single use. Substantial economies in the synthesis of labeled synthetic oligonucleotides are achieved by use of the cartridge.
REFERENCES:
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patent: 5262530 (1993-11-01), Andrus et al.
patent: 5298259 (1994-03-01), Lloyd et al.
patent: 5324483 (1994-06-01), Cody et al.
patent: 5429807 (1995-07-01), Matson et al.
Kaplan Bruce E.
Swiderski Piotr M.
City of Hope
Jones W. Gary
Rees Dianne
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