Disposable electronic assay device

Chemistry: analytical and immunological testing – Optical result – With reagent in absorbent or bibulous substrate

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Details

422 58, 422 8205, 422 8209, G01N 2178

Patent

active

055807941

ABSTRACT:
A disposable electronic assay device comprising card-like housing containing a sample receptor for receiving a sample of body fluid containing an analyte to be determined, a sample treatment element for reaction with sample fluid components to yield a physically detectable change which correlates with the amount of analyte in the sample, a detector responsive to the physically detectable change for producing an electrical signal which correlates with the amount of analyte in the sample, a signal processor connected to the detector for converting the electrical signal to a digital test result output, and visually readable output means connected to the signal processor for receiving and presenting the test result output. The signal processor can include an analog to digital conversion element for converting an analog reflectance or transmission output signal to a digital reflectance output, processor for converting the digital reflectance or transmission output to a digital test result output. The sample treatment element can include, for example, in fluid communication, a separator for separating interfering substances from the sample, a sample developer for converting the analyte in the sample to a physically detectable substance in an amount which correlates with the amount of the analyte. The sample development element can comprise bibulous material having a sample reaction zone containing reaction chemistry for reacting specifically with the analyte and producing a product with a physically detectable label, the amount of which correlate with the amount of analyte, and a detection zone positioned for interaction with the detector.

REFERENCES:
patent: 4627445 (1986-12-01), Garcia et al.
patent: 4806312 (1989-02-01), Greenquist

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