Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-03-30
1997-12-16
Chin, Christopher L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
422 55, 422 57, 422 58, 435 792, 435 793, 435 794, 4352871, 4352872, 4352879, 4352884, 4352885, 435810, 436164, 436172, 436514, 436518, 436524, 436527, 436528, 436537, 436805, 436807, 436808, 436810, G01N 3353, G01N 33558
Patent
active
056984065
ABSTRACT:
A disposable diagnostic device and method of its use are provided. The device comprises a housing containing first and second flow paths orthogonal to each other. The first flow path commences at a sample addition port and continues through a transport channel which feeds sample to an incubation area by means of capillary flow. The incubation area comprises a signal producing system and is underneath an optically-clear window. The first flow path terminates in a top waste reservoir which receives sample and wash fluid. The second flow path begins on one side of the incubation area at an inlet port over a side reagent reservoir. Liquid flows along the second flow path from the side reagent reservoir across the incubation area into the side waste reservoir. The incubation area may comprise agitation means for homogenous dispersion of reagent into liquid. Various reagents of a signal producing system may be contained within the device and the necessary liquids added automatically by appropriate instrumentation, so as to have the assay carried out automatically, without technician involvement, providing an accurate and sensitive determination.
REFERENCES:
patent: 4918025 (1990-04-01), Grenner
patent: 5164598 (1992-11-01), Hillman et al.
patent: 5207988 (1993-05-01), Lucas
patent: 5399486 (1995-03-01), Cathey et al.
patent: 5503985 (1996-04-01), Cathey et al.
Cathey Cheryl A.
Langford Jeffrey D.
Saul Tom
Schwartz Henry L.
Biocircuits Corporation
Chin Christopher L.
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