Disposable device for recovery, and if appropriate analysis, of

Surgery – Means and methods for collecting body fluids or waste material – Receptacle attached to or inserted within body to receive...

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Details

600574, 600582, A61M 100

Patent

active

058301992

DESCRIPTION:

BRIEF SUMMARY
BACKGROUND OF THE INVENTION

The present invention relates to the recovery, and if appropriate the analysis, of a body fluid directly from an elongate intracorporeal cavity, and by way of a non-limiting example the present invention will be introduced, defined and explained with reference to the recovery of the cervical mucosa in the vaginal cavity of women for detection of the period of fertility.
In order to determine the periods of fertility in women, it is known, and it has been proposed, to detect and monitor the presence and/or concentration of certain biochemical or biological constituents of said mucus, such as a peroxidase or a compound having a peroxidase activity, or such as a mucopolysaccharide or a glycoprotein, by using reagents or colored reagent systems, for example, in the former case, an oxidation-reduction compound, of which at least the oxidized form is colored, for example guaiacol, and in the latter case safranin.
The solutions which have been proposed for the use of such reagents or reactive systems have generally been rudimentary and have in practice been difficult for women to put into use, namely: recovering the mucus, such as a swab, then bringing said element into contact, outside the vaginal cavity, with the reagent in liquid form; the reagent, and withdrawing said tampon after a certain time, and observing the color, or the change of color, of the reagent on the absorbent tampon.
All these relatively rudimentary solutions are not adapted to an everyday use consistent with the personal hygiene practices of women.
As regards taking samples of body fluids or secretions, independently of their biochemical or biological analysis subsequent to or concomitant with the sampling, there are, in brief, two types of solution currently envisaged.
The first consists in recovering said fluids or secretions extracorporeally, at the actual site of their excretion, or in the vicinity of said site, on any suitable support or means for recovery. A solution of this kind has been described in DE-A-33 27 444, wherein a urine recovery device is disclosed, said device being provided with lips to sealingly surround the feminine urethral meatus, and comprising collection means for the body fluid and nonreturn means to prevent the collected liquid from leaking out from the collection means. However, this solution appears inappropriate when the fluid or secretion remains to all intents and purposes inside the body, such as the cervical mucus inside the vagina.
The second consists in recovering said fluids or secretions intracorporeally, within the intracorporeal cavity itself. This presupposes the use of devices or means for recovery which are adapted to be introduced into, kept inside, and withdrawn from the intracorporeal cavity. At present, the devices which are on the market or are described in the available literature are essentially adapted for the recovery of cells or cell samples.


SUMMARY OF THE INVENTION

The subject of the present invention is a disposable device, of the intracorporeal type, which is adapted specifically for the collection of body fluids or liquids.
The device according to the invention comprises in a general manner, collection means for recovering a body liquid, mounted or integrated into the device, extending along the length of the latter, and nonreturn means for the collected body liquid, said means closing the collection means when the liquid flows in the device in an opposite direction to that of collection, and further comprising fitted and held directly in contact with the inner wall of an elongate intracorporeal cavity, having a first open end, termed the neck, and a second closed end, termed the base; this conduit element is sufficiently stiff along its length to be pushed via its base, by any suitable means, including manually, and thereby introduced via its neck into the intracorporeal cavity for recovery purposes; and the structuring or the materials of the outer surface of the conduit element are chosen to be, or to remain, biocompatible with the inner wall of th

REFERENCES:
patent: 3651810 (1972-03-01), Ormerod
patent: 3683914 (1972-08-01), Crowley
patent: 3958561 (1976-05-01), Bucalo
patent: 5125118 (1992-06-01), Green
patent: 5231992 (1993-08-01), Leon

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