Display of receptors and analysis of binding interactions...

Chemistry: analytical and immunological testing – Biospecific ligand binding assay

Reexamination Certificate

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C435S007210, C435S069500, C435S252300, C536S024200, C536S023500, C530S402000

Reexamination Certificate

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07109041

ABSTRACT:
A display and method of preparing 7-transmembrane and other receptors for real-time kinetic analysis of binding interactions. The invention includes display on beads and in micelles for multi-well and flow cytometric analysis. The invention is useful for ligand discovery and drug action discovery, and G-protein response in particular.

REFERENCES:
patent: 4275149 (1981-06-01), Litman et al.
patent: 4665020 (1987-05-01), Saunders
patent: 5405784 (1995-04-01), Van Hoegaerden
patent: 5583010 (1996-12-01), Baumbach et al.
patent: 5601992 (1997-02-01), Lerner et al.
patent: 5639603 (1997-06-01), Dower et al.
patent: 5698685 (1997-12-01), Summerton et al.
patent: 5747349 (1998-05-01), van den Engh et al.
Fulton, RJ et al., Clinical Chemistry 43(9)1749-1756, 1997.
Sarvazyan-NA et al., Biochemistry 41(12858-12867)2002.
Eppler, MC et al., J. Biol. Chem. 267:22(15603-15612)92.
Wang, Ning and Donald E. Ingber, “Probing Transmembrane Mechanical Coupling and Cytomechanics Using Magnetic Twisting Cytometry,” Biochem. Cell Bio. vol. 73, pp. 327-335.
Sklar, Larry A., et al., “Regulation of Ligand-Receptor Dynamics by Guanine Nucleotides”, Journal of Biological Chemistry, vol. 262, No. 1, pp. 135-139, Jan. 5, 1987.
Sklar, Larry A. et al., “Non-cellular Display for Real Time Flow Cytometric Analysis of Seven Transmembrane Receptors”BiotechniquesMay 2000;28(5):976-80, 982-5.

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