Dispersion comprising a non-ionic emulsifier

Details Dispersion comprising a non-ionic emulsifier Dispersion comprising a non-ionic emulsifier

2006-02-14

2006-02-14

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S489000

Reexamination Certificate

active

06998140

ABSTRACT:
The invention relates to a dispersion suitable for use as coating agent and binder for pharmaceutical forms, having a solids content of 10–70% by weight consisting ofa) from 90 to 99% by weight of a methacrylate copolymer consisting of at least 90% by weight of (meth)acrylate monomers containing neutral radicals and having a glass transition temperature Tg of from −20° C. to +20° C. as determined by the DSC method, andb) 1–10% by weight of a nonionic emulsifier having an HLB of from 15.2 to 17.3.

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Achim Göpferich, et al., Journal of Controlled Release, vol. 18, No. 2, pp. 133-144, “The Influence of Endogenous Surfactant on the Structure and Drug-Release Properties of Eudragit NE30D-Matrices”, Feb. 1992.

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