Dispersing agents for use with hydrofluoroalkane propellants

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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Details

424 43, 424 45, 424 46, 514458, 514772, 514786, 514975, A61K 3121

Patent

active

055020763

ABSTRACT:
Vitamin E acetate, C.sub.3 -linked triesters, glycerin, t-butanol, and transesterified oil/polyethylene glycol are effective dispersing agents for use with hydrofluoroalkanes. Effective amounts of the above are effective in suspending medicaments which are useful in inhalation aerosols, and especially meter-dose inhalers.

REFERENCES:
patent: 4201778 (1980-05-01), Draper
patent: 4472393 (1984-09-01), Shapiro
patent: 4525341 (1985-06-01), Deihl
patent: 4906453 (1990-03-01), Tsoucalas
patent: 4983628 (1991-01-01), Frenette et al.
patent: 5124395 (1992-06-01), Abramowski et al.
patent: 5188748 (1993-02-01), Arnaud et al.
patent: 5266308 (1993-11-01), Lee et al.

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