Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Reexamination Certificate
2011-04-05
2011-04-05
Azpuru, Carlos A (Department: 1617)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
C977S797000, C977S799000, C977S801000
Reexamination Certificate
active
07919113
ABSTRACT:
A formulation containing one or more lipophilic agents, methods of making and using the formulation are described herein. The formulation is formed by adding a pre-suspension concentrate composition to an aqueous medium. Upon contact with the aqueous medium, a solid nanoparticle suspension spontaneously forms. The resulting formulation is in the form of a microemulsion. The concentrate contains an amphiphilic solvent, a pharmaceutically acceptable solid carrier such as a solid fatty acid or ester, a surfactant, and an agent. Preferably the concentrate contains a combination of a surfactant with a high hydrophilic/lipophilic balance (HLB) of at least about 8 and a surfactant with a low HLB of less than about 5. The agent is preferably a lipophilic drug and other lipophilic ingredient, such as vitamins. The composition is suitable for use in medical and non-medical applications. The microemuslions described herein have increased stability was compared to the prior art.
REFERENCES:
patent: 5342625 (1994-08-01), Hauer et al.
patent: 5583105 (1996-12-01), Kovacs et al.
patent: 5603951 (1997-02-01), Woo
patent: 5614491 (1997-03-01), Walch et al.
patent: 5639474 (1997-06-01), Woo
patent: 5716637 (1998-02-01), Anselem et al.
patent: 5741512 (1998-04-01), Hauer et al.
patent: 5756450 (1998-05-01), Hahn et al.
patent: 5798333 (1998-08-01), Sherman
patent: 5827822 (1998-10-01), Floc'h et al.
patent: 6004580 (1999-12-01), Backlund et al.
patent: 6028067 (2000-02-01), Hong et al.
patent: 7026290 (2006-04-01), Domb
patent: 0760237 (1997-03-01), None
patent: WO 96/13273 (1996-05-01), None
patent: WO 97/04795 (1997-02-01), None
patent: WO 97/19692 (1997-06-01), None
patent: WO 98/33512 (1998-08-01), None
The Merck Index, The Merck Index, 12th ed. Merck & Co. Inc. 1996.
Azpuru Carlos A
Pabst Patent Group LLP
Yissum Research Development Company of the Hebrew University of
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