Dispensing mechanism, dispensing apparatus and dispensing...

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

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C422S501000, C073S864010

Reexamination Certificate

active

08030093

ABSTRACT:
There is provided a dispensing mechanism for a liquid to be dispensed that does not damage microspherical bodies such as an erythrocyte and a liposome in the liquid to be dispensed when the liquid to be dispensed such as a sample and test liquid is sucked/discharged with a pipette.When a liquid to be dispensed of a sample or a test liquid being an object to be measured includes a microspherical body, and the microspherical body is one with such property that it may be damaged when being contacted with a liquid having an osmotic pressure different from that of the liquid in the microspherical body, the damage of the microspherical body is prevented by sequentially sucking a gas, a solution exhibiting an osmotic pressure that does not damage the microspherical body in the liquid to be dispensed and not having a bad effect on the measurement, the gas, and the liquid to be dispensed in a pipette the inside of which is filled with a liquid, because the pipette inside wall is substituted with the solution having an osmotic pressure that does not damage the microspherical body.

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International Search Report for International Application No. PCT/JP2006/308562 dated Aug. 1, 2006.
Monroe, Dan, “Novel Liposome Immunoassays for Detecting Antigens, Antibodies, and Haptens,” J. of Liposome Research, 1989-90, 1(3), pp. 339-377 (specification, p. 15).
Yamamoto, Sachiko, et al. , “Automated Homogenous Liposome-Based Assay System for Total Complement Activity,” Clin. Chem., 1995, 41/4, pp. 586-590 (specification p. 15).

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