Disopyramide compounds for conjugating proteins used in immunoas

Details Disopyramide compounds for conjugating proteins used in immunoas Disopyramide compounds for conjugating proteins used in immunoas

1980-02-11

1981-09-08

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435 7, 260112R, 260112B, 260121, 424 12, 424 85, 546333, C12N 996, G01N 3354, C02D21100

Patent

active

042885531

ABSTRACT:
Novel carboxyalkylated disopyramides (NORPACE.RTM.) are provided as precursors for conjugating proteins, either antigenic for the preparation of antibodies or enzymatic for the preparation of enzyme conjugates, which antibodies and enzyme conjugates find use as reagents in immunoassays. The combination of antibodies and enzyme conjugates provide for sensitive, accurate, rapid assays for disopyramide without interference from closely analogous compounds, such as methadone or disopyramides metabolites.

REFERENCES:
patent: 3225054 (1965-12-01), Cusic
patent: 3852157 (1974-12-01), Rubenstein et al.
patent: 3878187 (1975-04-01), Schneider et al.
patent: 4026879 (1977-05-01), Spector
patent: 4235969 (1980-11-01), Singh et al.

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