Disodium 4-chlorophenylthiomethylenebisphosphonate monohydrate,

Details Disodium 4-chlorophenylthiomethylenebisphosphonate monohydrate, Disodium 4-chlorophenylthiomethylenebisphosphonate monohydrate,

1994-12-28

1998-04-14

Conrad, Joseph

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus acids or salts thereof

C07F 928

Patent

active

057393818

ABSTRACT:
The present invention relates to disodium 4-chlorophenylthiomethylenebisphosphonate monohydrate.
The invention further relates to the method of preparing this monohydrate.
The invention further relates to the pharmaceutical compositions in which disodium tiludronate monohydrate is present as the active principle.

REFERENCES:
patent: 4746654 (1988-05-01), Breliere et al.
patent: 4876248 (1989-10-01), Breliere et al.
patent: 4922007 (1990-05-01), Kieczykowski et al.
Bonnery et al., Bulletin de la Societe Chimique de France, No. 1, 1988; pp. 49-56.

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