Measuring and testing – Instrument mechanism or transmission – Rate of change
Patent
1986-12-11
1988-07-05
Levy, Stewart J.
Measuring and testing
Instrument mechanism or transmission
Rate of change
G01N 1900
Patent
active
047546573
DESCRIPTION:
BRIEF SUMMARY
The invention relates to a disintegration testing device for solid substance samples which disintegrate in a solvent, in particular tablets and the like, which includes a detachable disintegration cage which may be submerged into a solvent in a container, wherein the disintegration cage contains a sample held in position with a disk so that an electrical signal is generated when the sample is disintegrated.
A disintegration testing device already is known in which a water reservoir is provided for a housing, which reservoir is provided with a heating element for heating the water in the reservoir to a predetermined temperature. In the water bath several containers are filled with solvents, e.g. as a substitute for gastric juice. A disintegration cage which is formed out of a plurality of tubes each being closed at the bottom by a screen, is inserted into each container. A tablet is inserted into each tube as a sample and each is loaded with a disk of plastic material. In each tube electric lines are provided which are short circuited upon disintegration of the sample and in this manner the disintegration of the tablet is indicated. Electric lines are provided between the disintegration cages and the respective mounts for feeding the signals indicating the disintegration to an electronic recording device.
It appeared that the disintegration cages with the connecting cables are susceptible to failure and that the handling thereof is time-consuming. This is in particular true with regard to the cleaning of the disintegration cages and the charging of the cages with the sample.
The invention, therefore, is based on solving the problem of providing a disintegration testing device having a low susceptability of failure and being easy to handle.
According to the present invention these problems are solved in the disintegration testing device of the present invention as described hereinbelow.
The disintegration testing device according to the present invention has the advantage that it can be charged with samples in an easy manner since no electric lines protrude from the tubes of the disintegration cage. The disintegration cages can be cleaned in an easy manner since no wire connection exists between the disintegration cage and the actual disintegration testing device and/or the recording device, respectively.
Hall generators may be arranged laterally at the bottom part of the disintegration cage, e.g at each tube, and at respective positions a magnet may also be arranged laterally with respect to the disk. However, it appears to be advantageous to arrange the magnet at the bottom side of the disk and to arrange the Hall generator at a screen closing the disintegration cage at the bottom, preferably at the bottom side of the screen.
A particularly easy handling properly of the disintegration cage is realized when the energy and/or signals are transmitted in a wireless manner between a transmission unit fixed to a mount and the disintegration cage. The wireless transmission of signals is preferably effected using opto-electronic elements, preferably by means of an infrared light bridge. In this case the signals indicating the disintegration of a sample are first transmitted from the disintegration cage to the transmission unit and then are fed to the recording device. Furthermore, it turns out to be advantageous to transmit the energy for the power supply of the electric circuits arranged in the disintegration cage using a high-frequency emitter provided in the transmission unit and a high-frequency receiver arranged in the disintegration cage.
A particularly low-cost embodiment of the disintegration device, however, results when effecting the transmission of energy and/or signals between the transmission unit and the dissolution cage using electrical contacts. By the transmission of energy and signals in a wireless manner or by the use of electrical contacts it is guaranteed that no wire connection exists between the disintegration cage and the actual disintegration testing device so that the disintegration cage
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Erweka Apparatebau GmbH
Levy Stewart J.
Roskos Joseph W.
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