Disinfectant dye removal from blood and blood fractions using a

Details Disinfectant dye removal from blood and blood fractions using a Disinfectant dye removal from blood and blood fractions using a

1996-09-17

1999-01-12

Saucier, Sandra E.

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

210633, 210660, A01N 102

Patent

active

058586415

ABSTRACT:
A process for removing disinfectant dye such as methylene blue from blood, a liquid blood fraction or other perishable liquid to which disinfectant dye has been added. The process employs a filter of polyvinyl alcohol-acetal copolymer. This material shows exceptional avidity for disinfectant dyes, readily removing them from blood or blood fractions while having little or no effect on subsequent chemicals analysis of the treated material. The filter material is a porous matrix that releases no particles or fines into the blood product, and its white color readily shows the capture of the blue dye. Disinfectant dyes are used to extend the shelf life of platelet concentrates with the dyes being removed by a PVAA filter prior to transfusion into a patient. Also, triglycerides may also be removed from plasma or other solutions by passage through a porous matrix of poly(vinyl alcohol-acetal) copolymer.

REFERENCES:
patent: 4305390 (1981-12-01), Swartz
patent: 4548927 (1985-10-01), Eaton
patent: 5639376 (1997-06-01), Lee et al.
"The Pharmacological Basis of Therapeutics--Germicides, Fungicides and Parasiticides", Goodman & Gilman--1941.

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