Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-11-20
2007-11-20
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091100
Reexamination Certificate
active
11333352
ABSTRACT:
An object of the present invention is to provide an allele specific primer which is accompanied by less possibility of the false positive and enables definite discrimination when a base immediately adjacent to on the 3′ side of a target SNP base is A, while a base adjacent with one base spaced apart is T.According to the present invention, the 3′ end base is designed to be the base corresponding to SNP; the second base from the 3′ end to be C; the third base from the 3′ end to be any one of T, C or G; and the base sequence of from the fourth from the 3′ end to the 5′ end base to be complementary to the sequence of from a base three bases away from the target SNP base on the 3′ side to a desired base.
REFERENCES:
patent: 6750018 (2004-06-01), Kambara et al.
patent: 6794133 (2004-09-01), Ausubel et al.
patent: 2003/0049628 (2003-03-01), Kambara et al.
patent: 2003/0148301 (2003-08-01), Aono et al.
patent: 2003/0186314 (2003-10-01), Kambara et al.
patent: 2004/0197803 (2004-10-01), Yaku et al.
patent: 2002-101899 (2002-04-01), None
patent: 2004-248635 (2004-09-01), None
patent: 2004-248635 (2004-09-01), None
patent: 2005-65688 (2005-03-01), None
patent: WO 01/42498 (2001-06-01), None
Delrio-Lafreniere et al. (“Simultaneous allele-specific amplification: a strategy using modified primer-template mismatches for SNP detection—application to prothrombin 20210A (factor II) and factor V Leiden (1691A) gene mutations” Mol Diagn. Sep. 2001;6(3):201-9).
U.S. Appl. No. 11/203,417, filed Aug. 15, 2005, Yaku et al.
U.S. Appl. No. 11/363,953, filed Mar. 1, 2006, Yaku et al.
U.S. Appl. No. 11/471,646, filed Jun. 21, 2006, Yaku et al.
U.S. Appl. No. 11/488,635, filed Jul. 19, 2006, Yaku et al.
U.S. Appl. No. 11/488,633, filed Jul. 19, 2006, Yaku et al.
U.S. Appl. No. 11/489,582, filed Jul. 20, 2006, Yaku et al.
U.S. Appl. No. 11/489,583, filed Jul. 20, 2006, Yaku et al.
U.S. Appl. No. 11/633,587, filed Dec. 5, 2006, Yaku et al.
U.S. Appl. No. 11/633,584, filed Dec. 5, 2006, Yaku et al.
U.S. Appl. No. 11/607,900, filed Dec. 4, 2006, Yaku et al.
U.S. Appl. No. 11/607,907, filed Dec. 4, 2006, Yaku et al.
U.S. Appl. No. 11/333,352, filed Jan. 18, 2006, Yaku et al.
U.S. Appl. No. 11/363,953, filed Mar. 1, 1006, Yaku et al.
Japanese Office Action issued in corresponding Japanese Patent Application No. JP 2006-039784, dated Jul. 21, 2006.
U.S. Office Action issued in corresponding U.S. Appl. No. 11/633,584, mailed Jun. 22, 2007.
U.S. Office Action issued in corresponding U.S. Appl. No. 11/471,646, mailed Jun. 26, 2007.
Delrio-LaFreniere et al., “Simultaneous Allele-specific Amplification: A Strategy Using Modified Primer-template Mismatches for SNP Detection-Application to Prothrombin 20210A (Factor II) and Factor V Leiden (1691A) Gene Mutations,” Molecular Diagnosis vol. 6, No. 3, pp. 201-209, 2001, Minneapolis Minnesota.
Oka Hiroaki
Yaku Hidenobu
Yukimasa Tetsuo
Babic Christopher M.
Horlick Kenneth R.
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