Discrete nano-textured structures in biomolecular arrays,...

Details Discrete nano-textured structures in biomolecular arrays,... Discrete nano-textured structures in biomolecular arrays,...

2005-11-08

2005-11-08

Ghyka, Alexander (Department: 2812)

Semiconductor device manufacturing: process

Having biomaterial component or integrated with living organism

C435S006120, C435S007100

Reexamination Certificate

active

06962822

ABSTRACT:
A biomolecular array includes a substrate across which is distributed an array of discrete regions of a porous substance. The porous substance is designed to bind chemical targets useful in biotechnology applications, such as gene expression, protein, antibody, and antigen experiments. The regions are preferably optically isolated from each other and may be shaped to enhance detection of optical radiation emanating from the porous substance, e.g., as a result of irradiation of the regions with ultraviolet light. The discrete regions may be configured as microscopic wells within the substrate, or they may reside on top of the substrate in the form of microscopic mesas.

REFERENCES:
patent: 5895263 (1999-04-01), Carter et al.
patent: 6143496 (2000-11-01), Brown et al.
patent: 6610499 (2003-08-01), Fulwyler et al.
patent: 201 21 709 (2003-05-01), None
patent: 0 816 827 (1998-01-01), None
patent: 1 267 169 (2002-12-01), None
patent: WO 98/28075 (1998-07-01), None
patent: WO 99/41007 (1999-08-01), None
patent: WO 01/19505 (2001-03-01), None
patent: WO 01/43870 (2001-06-01), None
patent: WO 01/51658 (2001-07-01), None
patent: WO 02/43937 (2002-06-01), None
patent: WO 01/50131 (2002-07-01), None
Chen et al., “Three-Dimensional Probe Carriers,” U.S. patent application publication No. 2002/0055111, May 9, 2002, application No. 09/938,798.
Hess et al., “Apparatus for Assay, Synthesis and Storage, and Methods of Manufacture, Use, and Manipulation Thereof,” U.S. patent Appl. Publ. No. 2002/0094533, Jul. 18, 2002, Appl. No. 09/975,496.
Gunther Mayer et al., “Nanotiterplates for Screening and Synthesis”, BioMethods, vol. 10, 1999, pp. 75-128.
Samuel K. Moore, “Making Chips to Probe Genes”, IEEE Spectrum, Mar. 2001, pp. 54-60.
Michael C. Pirrung, “How to make a DNA Chip”, Agnew Chem. Int. Ed., 2002, vol. 41, pp. 1276-1289.

Affiliated with

Also associated with

Rating

Discrete nano-textured structures in biomolecular arrays,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Discrete nano-textured structures in biomolecular arrays,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Discrete nano-textured structures in biomolecular arrays,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3480266