Discrete drop dispensing device and method of use

Details Discrete drop dispensing device and method of use Discrete drop dispensing device and method of use

2008-07-10

2010-10-19

Therkorn, Ernest G (Department: 1797)

Liquid purification or separation

With means to add treating material

Chromatography

C210S656000, C222S199000, C222S420000, C239S004000, C239S102100, C422S070000, C422S105000

Reexamination Certificate

active

07815798

ABSTRACT:
A discrete drop dispensing device comprises a substrate comprising an upper surface and a lower surface and orifices extending from the upper surface to the lower surface, adapted to receive a fluid at a flow rate. The discrete drop dispensing device also comprises an oscillator disposed adjacent to the substrate and configured to vibrate the substrate to expel drops having a substantially equal volume of the fluid. The flow rate is substantially identical to a drop dispensing rate. A method and a device for performing liquid chromatography are also described. The method comprises automatically adjusting the drop dispensing rate to a change in the flow rate or a change in a composition of a mobile phase of the fluid.

REFERENCES:
patent: 4934564 (1990-06-01), Piatt
patent: 6509562 (2003-01-01), Yang et al.
patent: 6540153 (2003-04-01), Ivri
patent: 6569385 (2003-05-01), Little et al.
patent: 6917165 (2005-07-01), Hopwood et al.
patent: 2005/0195393 (2005-09-01), Karanassios
patent: 2006/0176341 (2006-08-01), Juch et al.

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