Discontinuous countercurrent chromatographic process and apparat

Details Discontinuous countercurrent chromatographic process and apparat Discontinuous countercurrent chromatographic process and apparat

1995-11-30

1997-05-20

Therkorn, Ernest G.

Liquid purification or separation

Processes

Chromatography

210656, 2101982, B01D 1508

Patent

active

056309430

ABSTRACT:
A preparative chromatographic cyclical process comprising, at steady state: establishing a figure-of-eight circulating chromatographic profile between two chromatographic columns with the provision that said chromatographic profile never passes through a pump; discontinuously and periodically injecting a sample comprising at least two components, into said circulating profile; and collecting, discontinuously and periodically, at least two enriched fractions from said circulating profile, the apparatus for conducting this process comprising only two chromatographic columns, at least one solvent pump, an injection pump, two 4-way valves, and conduit communicating said columns and the two 4-way valves in the form of a figure-of-eight pattern without traversing a pump, and conduit communicating said at least one solvent pump and at least one of said columns.

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