Dirofilaria immitis Gp29 proteins and uses thereof

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Oxidoreductases

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435192, 530403, C12N 1553, A61K 3844

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active

056185324

ABSTRACT:
The present invention relates to D. immitis Gp29 proteins, nucleic acid molecules having sequences that encode such proteins, antibodies raised against such proteins and inhibitors of D. immitis glutathione peroxidase. The present invention also includes methods to obtain such nucleic acid molecules, proteins, antibodies and inhibitors. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies and inhibitors as well as their use to protect animals from disease caused by parasitic helminths, such as heartworm.

REFERENCES:
Flohe et al., pp. 159-169 1971, Hoppe-Seyler's Z. Physiol. Chem., vol. 352.
Maizels et al., pp. 249-254, 1991, Immunol. Letters, vol. 30.
Maizels et al., pp. 213-228, 1989, Mol. Biochem. Parasitol., vol. 32.
Ogilvie et al., pp. 607-618, 1990, J. Parasitol., vol. 76.
Selkirk et al., pp. 263-281, 1992, Immunobiol., vol. 184.
Selkirk et al., pp. 373-380, 1990, Acta Tropica, vol. 47.
Selkirk et al., pp. 31-43, 1990, Mol. Biochem. Parasitol., vol. 42.
Selkirk et al., pp. 91-102, 1987, Biochem. Soc. Symp., vol. 53.
Takahashi et al., pp. 677-686, 1987, Arch. Biochem. Biophys., vol. 256.
Waxman, pp. 6449-6454, 1990, Cancer Res., vol. 50.
Zvelebil et al., pp. 145-154, 1993, Mol. Biochem. Parasitol., vol. 58.
Callahan et al., pp. 245-252, 1991, Mol. Biochem. Parasitol., vol. 49.
Cookson et al., pp. 155-160, 1993, Mol. Biochem. Parasitol., vol. 58.
Cookson et al., pp. 5837-5841, 1992, Proc. Natl. Acad. Sci., vol. 89.
Devaney et al., pp. 75-87, 1991, Para. Immunol., vol. 13.
Devaney et al., pp. 365-372, 1990, Acta Tropica, vol. 47.
EMBL/GenBank Database # NCBI gi:452448, unpublished, submitted Dec. 22, 1993.

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