Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Oxidoreductases
Patent
1995-06-05
1997-04-08
Hendricks, Keith D.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Oxidoreductases
435192, 530403, C12N 1553, A61K 3844
Patent
active
056185324
ABSTRACT:
The present invention relates to D. immitis Gp29 proteins, nucleic acid molecules having sequences that encode such proteins, antibodies raised against such proteins and inhibitors of D. immitis glutathione peroxidase. The present invention also includes methods to obtain such nucleic acid molecules, proteins, antibodies and inhibitors. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies and inhibitors as well as their use to protect animals from disease caused by parasitic helminths, such as heartworm.
REFERENCES:
Flohe et al., pp. 159-169 1971, Hoppe-Seyler's Z. Physiol. Chem., vol. 352.
Maizels et al., pp. 249-254, 1991, Immunol. Letters, vol. 30.
Maizels et al., pp. 213-228, 1989, Mol. Biochem. Parasitol., vol. 32.
Ogilvie et al., pp. 607-618, 1990, J. Parasitol., vol. 76.
Selkirk et al., pp. 263-281, 1992, Immunobiol., vol. 184.
Selkirk et al., pp. 373-380, 1990, Acta Tropica, vol. 47.
Selkirk et al., pp. 31-43, 1990, Mol. Biochem. Parasitol., vol. 42.
Selkirk et al., pp. 91-102, 1987, Biochem. Soc. Symp., vol. 53.
Takahashi et al., pp. 677-686, 1987, Arch. Biochem. Biophys., vol. 256.
Waxman, pp. 6449-6454, 1990, Cancer Res., vol. 50.
Zvelebil et al., pp. 145-154, 1993, Mol. Biochem. Parasitol., vol. 58.
Callahan et al., pp. 245-252, 1991, Mol. Biochem. Parasitol., vol. 49.
Cookson et al., pp. 155-160, 1993, Mol. Biochem. Parasitol., vol. 58.
Cookson et al., pp. 5837-5841, 1992, Proc. Natl. Acad. Sci., vol. 89.
Devaney et al., pp. 75-87, 1991, Para. Immunol., vol. 13.
Devaney et al., pp. 365-372, 1990, Acta Tropica, vol. 47.
EMBL/GenBank Database # NCBI gi:452448, unpublished, submitted Dec. 22, 1993.
Grieve Robert B.
Selkirk Murray E.
Tripp Cynthia A.
Hendricks Keith D.
Heska Corporation
LandOfFree
Dirofilaria immitis Gp29 proteins and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dirofilaria immitis Gp29 proteins and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dirofilaria immitis Gp29 proteins and uses thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2396390