Directly-pressable ascorbic acid-containing granulates

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic polymer or copolymer

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A61K 31365

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active

042039975

ABSTRACT:
An ascorbic acid granulate comprising 90-93 wt. % of ascorbic acid, 5-9 wt. % of a sugar or sugar alcohol and about 1-2 wt. % of a lubricant may be directly compressed.

REFERENCES:
patent: 3200039 (1965-08-01), Thompson
patent: 3247065 (1966-04-01), Koff
patent: 3384546 (1968-05-01), Palermo
patent: 3446894 (1969-05-01), Magid
patent: 3453368 (1969-07-01), Magid
patent: 3873713 (1975-03-01), Haas et al.
patent: 4036948 (1977-07-01), Kitamori et al.
Am. Pharmacy (1947)-Lyman (ed.), pp. 218-219.
Remington's Pharmaceutical Sciences 13th Ed., p. 1407-(1965).
Vitamin C:Its Molecular Biology and Medical Potential-Lewin-Academic Press, N.Y.-p. 16 (1976).

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