Directed in vitro differentiation of marrow stromal cells...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of co-culturing cells

Reexamination Certificate

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C435S325000, C435S366000

Reexamination Certificate

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07547545

ABSTRACT:
The invention relates to methods for inducing marrow stromal cells to differentiate into neural cells by way of increasing intracellular levels of cyclic AMP. The invention also encompasses methods of producing a neural cell by causing a marrow stromal cell to differentiate into a neural cell by increasing intracellular levels of cyclic AMP. Methods for treating a human patient in need of neural cells are also disclosed, as well as methods for treating a human patient having a disease, condition, or disorder of the central nervous system.

REFERENCES:
patent: WO 96-30031 (1996-10-01), None
patent: WO 99-43286 (1999-09-01), None
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