Direct-fed microbial

Details Direct-fed microbial Direct-fed microbial

2004-11-03

2008-12-30

Marx, Irene (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C424S093400, C426S061000

Reexamination Certificate

active

07470531

ABSTRACT:
An isolated microorganism comprising aPropionibacteriastrain. When the microorganism is fed to a ruminant, protein and fat levels in milk produced by the ruminant are increased, while body condition and milk production levels are maintained. When fed to the ruminant, the microorganism also has positive effects on various metabolic hormones and metabolites, e.g, an increase in energy balance, plasma non-esterified fatty acids levels, and plasma leptin level. Supplementation withpropionibacteriareduced dry matter intake but did not affect milk production in the cows. Therefore, thepropionibacteriaof the invention made the cows more energy efficient as cows produced the same amount of milk, yet consumed less dry matter.

REFERENCES:
patent: 4981705 (1991-01-01), Tomes
patent: 5026647 (1991-06-01), Tomes et al.
patent: 5139777 (1992-08-01), Ott et al.
patent: 5501857 (1996-03-01), Zimmer
patent: 5529793 (1996-06-01), Garner et al.
patent: 5534271 (1996-07-01), Ware et al.
patent: 5945333 (1999-08-01), Rehberger
patent: 6120810 (2000-09-01), Rehberger et al.
patent: 6221650 (2001-04-01), Rehberger
patent: 6455063 (2002-09-01), Rehberger
patent: 2 253 426 (1972-10-01), None
patent: WO 99/53775 (1999-10-01), None
Amaral-Phillips, D.M., A.D. McGilliard, G.L. Lindberg, J.J. Veenhuizen, J.J., and J. W. Young. 1993. Effects of decreased availability of glucose for dairy cows. J. Dairy Sci. 76:752-761.
Beam, S.W. and W. R. Butler. 1998. Energy Balance, metabolic hormones, and early postpartum follicular development in dairy cows fed prilled lipid. J. Dairy Sci. 81:121-131.
Canfield, R.W. and W.R. Butler. 1991. Energy balance, first ovulation and the effects of naloxone on LH secretion in early postpartum dairy cattle. J. Anim. Sci. 69: 740-746.
Carrol, D.J., M.J. Jerred, R.R. Grummer, D.K. Combs, R.A. Pierson, and E.R. Hauser. 1990. Effect of fat supplementation and immature alfalfa to concentrate ratio on plasma progesterone, energy balance, and reproductive traits of cattle. J. Dairy Sci 73:2855-2863.
Gong, J.G., D. McBride, T.A. Bramley, and R. Webb. 1994. Effects of recombinant bovine somatotropin, insulin-like growth factor I and insulin on bovine granulosa cell steroidogenesis in vitro. J. Anim. Sci. 143:157-164.
Grummer, R.R. and D.J. Carroll. 1991. Effects of dietary fat on metabolic disorders and reproductive performance of dairy cattle. J. Anim. Sci. 69: 3838-3852.
Grummer, R.R. and D.J. Carroll. 1988. A review of lipoprotein cholesterol metabolism: importance to ovarian function. J. Anim. Sci. 66:3160-3173.
Hawkins, G.E., K.A. Cummins, M. Silverio and J.J. Jilek. 1985. Physiological effects of whole cottonseed in the diet of lactating dairy cows. J. Dairy Sci .68:2608-2614.
Huhtanen, P., H. Miettinen, and M. Ylinen. 1993. Effect of increasing ruminal butyrate on milk yield and blood constituents in dairy cows fed a grass silage-based diet. J. Dairy Sci. 76:1114-1124.
Jonsson, N.N., R.C. Daniel, D. Mayer and R. Verrall. 1998. Effects of oral dosing with calcium propionate on total calcium and glucose concentrations in the plasma of the cow. Zentralbl Verinarmed A 45:127-136 (Abstract only).
Kimura, M., Nakao, T., Moriyoshi, M. and Kwata, K. 1987. Luteal phase deficiency as a possible cause of repeat breeding in dairy cows. Brit. Vet. J. 143:560-566.
Koprowski, J.A. and H.A. Tucker. 1973. Bovine serum growth hormone, corticoids and insulin during lactation. Endocrinology 93:645-651.
Kronfeld, D.S., S. Donoghue, J.M.Naylor, K. Johnson and C.A. Bradley. 1980. Metabolic effects of feeding protected tallow to dairy cows. J. Dairy Sci. 63:545552.
McArdle, C.A., Kohl, C., Rieger, K., and Wehrenberg, U. 1991. Effects of gonadotropins, insulin, and insulin like growth factor I on ovarian oxytocin and progesterone production. Mol Cell Endocrinol. 78:211-220.
McArdle, C.A. and Holtorf, A.P. 1989. Oxytocin and progesterone release from bovine corpus luteal cells in culture: Effects of insulin-like growth factor I, insulin and prostaglandins. Endocrinology 124:1278-1286.
Oshio, S.,I. . Tahata and H. Minato. 1987. Effects of diets differing in ratios of roughage to concentrate on microflora in the rumen of heifers. J. Gen. Appl. Microbiol. 33:99.
Ronge, H., Blum, J. Clement, C., Jans, F., Leuenberger, H., and Binder, H. 1988.
Saumande, J. 1991. Culture of bovine granulosa cells in a chemically defined serum-free medium: The effect of insulin and fibronectin on the response to FSH. J. Steroid Biochem. Mol. Biol. 38:189-196.
Schams, D., Koll, R., and Li, C.H. 1988. Insulin-like growth factor I stimulates oxytocin and progesterone production by bovine granulosa cells in culture. J. Endocrinol 116:97-100.
Sklan, D., U. Moallem and Y. Folman. 1991. Effect of feeding calcium soaps of fatty acids on production and reproductive responses in high producing lactating cows. J. Dairy Sci. 74:510-517.
Smith, et al. 1978. Effects of feeding protected tallow to dairy cows in early lactation. J. Dairy Sci. 61:747-756.
Spicer, L.J., A. Alpizar, and S.E. Ecternkamp. 1993. Effects of insulin, insulin-like growth factor 1, and gonadotropins on bovine granulosa cell proliferation, progesterone production, estradiol production, and (or) insulin-like growth factor I production in vitro. J. Anim. Sci. 71:1232-1241.
Spicer, L.J. and C.S. Chamberlain. 1998. Influence of cortisol on insulin- and insulinlike growth factor 1 (IGF-1)-induced steroid production and on IGF-1 receptors in cultured bovine granulosa cells and thecal cells. Endocrine 9:153-161.
Spicer, L.J., W.B. Tucker. and G.D. Adams. 1990. Insulin-like growth factor-I in dairy cows: Relationships among energy balance, body condition score, ovarian activity, and estrous behavior. J. Dairy Sci. 73:929-937.
Spicer, L.J., R.K. Vernon, W.B. Tucker, R.P. Wettemann, J.F. Hogue, and G.D. Adams 1993. Effects of inert fat on energy balance, plasma concentrations of hormones and reproduction in dairy cows. J. Dairy Sci. 76:2664-2673.
Staples, C.R. and W.W. Thatcher. 1990. Relationship between ovarian activity and energy status during the early postpartum period of high producing dairy cows. J. Dairy Sci. 73:938-947.
Talavera, F., C.S. Park and G.L. Williams. 1985. Relationships among dietary lipid intake, serum cholesterol and ovarian function in Holstein heifers. J. Anim. Sci. 60:1045-1051.
Villa-Godoy, A., T.L. Hughes, R.S. Emery, L.T. Chapin and R.L. Fogwell. 1988. Association between energy balance and luteal function in lactating cows. J. Dairy Sci. 71:1063-1072.
C.A. Davidson and T.G. Rehberger, Characterization ofPropionibacteriumIsolated from the Rumen of Lactating Dairy Cows, abstract book from the 95thGeneral Meeting of the American Society for Microbiology (1995).
King M et al: “Genetic analysis of the nitrate reductase gene fromPropionibacterium” Abstracts of the General Meeting of the American Society for Microbiology, vol. 94, No. 0, 1994, p. 363, XP009055171 & 94thGeneral Meeting of the American Society for Microbiology; Las Vegas, Nevada, USA, May 23-27, 1994; ISSN: 1060-2011, the whole document.
Kalantzopoulos G: “Fermented products with probiotic qualities” Anaerobe, vol. 3, No. 2-3, 1997, pp. 185-190, XP002348690, ISSN: 1075-9964, abstract.
Davidson C A et al: “Characterization ofPropionibacteriumisolated from the rumen of lactating dairy cows” Abstracts of the General Meeting of the American Society for Microbiology, vol. 95, No. 0, 1995, p. 318, XP009055170 & 95thGeneral Meeting of the American Society for Microbiology, Washington, D.C., USA, May 21-25, 1995, ISSN: 1060-2011, the whole document.
Johnson J L et al: “Cell wall composition and deoxyribonucleic acid similarities among the anaerobic coryneforms, classicalpropionibacteria, and strains ofArachnia propionica” Journal of Bacteriology, Mar. 1972, vol. 109, No. 3, Mar. 1972, pp. 1047-1066, XP002348691, ISSN: 0021-9193, abstract; tables 1, 3, 5.

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