Direct, externally imposed control of nucleic acids

Details Direct, externally imposed control of nucleic acids Direct, externally imposed control of nucleic acids

2005-10-11

2005-10-11

Riley, Jezia (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100, C435S091100, C435S091200, C435S287200, C536S022100, C536S023100, C536S024300, C536S024330

Reexamination Certificate

active

06953659

ABSTRACT:
Methods and compositions for rendering nucleic acids directly responsive to an external signal utilizing modulators that themselves respond to the external signal and are associated with the nucleic acid. In response to the external signal, the modulator alters physical properties of the specific nucleic acid molecule(s) with which it is associated, thereby altering the structural and functional properties thereof. The modulator may, for example, transfer applied energy to a nucleic acid, or to a portion of the nucleic acid, thereby changing the nucleic acid structure.

REFERENCES:
patent: 5283174 (1994-02-01), Arnold, Jr. et al.
patent: 6410235 (2002-06-01), Weindel et al.
patent: 6506564 (2003-01-01), Mirkin et al.
patent: 2002/0165191 (2002-11-01), Moonen
Kellogg et al Biotechniques vol. 16 No. 6 pp. 1134-1138 1994.

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