Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1992-12-18
1993-09-21
Ramsuer, Robert W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C07D41312
Patent
active
052470830
ABSTRACT:
Mycophenolate mofetil is made non-catalytically by refluxing mycophenolic acid with 2-morpholinoethanol in an inert organic solvent capable of azeotropic removal of water.
REFERENCES:
patent: 4753935 (1988-06-01), Nelson et al.
Wagner and Zook, Synthetic Organic Chemistry, (1953) pp. 480-481.
Morrison and Boyd "Organic Chemistry", Allyn & Bacon, Fifth Edition, Newton, Mass., pp. 841-843, 872-874. (1984).
Donegan Gregory
Knox Martin
Smith Dennis A.
Desjardins Cathleen
Lowin David A.
Moran Tom M.
Ramsuer Robert W.
Syntex (U.S.A.) Inc.
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