Direct delivery of anti-inflammatories to the proximal small bow

Details Direct delivery of anti-inflammatories to the proximal small bow Direct delivery of anti-inflammatories to the proximal small bow

1990-03-21

1992-06-09

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604264, 604270, A61M 3100

Patent

active

051203065

ABSTRACT:
Transpyloric treatment of small bowel inflammation (e.g. Crohn's disease) by topical application of anti-inflammatory agents such as 5-ASA, 4-ASA or 3-ASA has hitherto been by oral administration of tablets the accurate targeting of which, in the variable environment of the gut, has been impossible. Now, by using an enteric feeding tube, an effective amount of an agent like 5-ASA may be delivered directly to the inflamed segment fo the gastrointestinal tract in patients suffering from inflammatory bowel disease whereby the agent is brough into direct, topical contact with inflamed mucosa while avoiding prior degradation in the stomach.

REFERENCES:
patent: 3922339 (1975-11-01), Shear
patent: 4190716 (1980-02-01), Parkinson et al.
patent: 4211777 (1980-07-01), Chambers
patent: 4298595 (1981-11-01), Parkinson et al.
patent: 4312806 (1982-01-01), Lambert et al.
patent: 4440763 (1984-04-01), Lover
patent: 4496553 (1985-01-01), Halskov
patent: 4540685 (1985-09-01), Bauer
patent: 4631054 (1986-12-01), Kim
patent: 4632921 (1986-12-01), Bauer
patent: 4657900 (1987-04-01), Powell et al.
patent: 4663308 (1987-05-01), Saffran et al.
patent: 4664256 (1987-05-01), Halskov
patent: 4678807 (1987-07-01), Cotter et al.
patent: 4698059 (1987-10-01), Johnson
patent: 4753963 (1988-06-01), Jandacek et al.
patent: 4769014 (1988-09-01), Russo
Enteral Feeding Products--Jul. 1987--Ross Laboratories of Columbus, Ohio, USA (brochure).
Flexiflow Enteral Feeding Tube--Nov. 1985--Ross Laboratories of Columbus, Ohio USA (brochure).
Klotz et al., Drug Research, 35(I), No. 3 (1985) 636-639.

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