Dipyridamole-containing pharmaceutical form

Details Dipyridamole-containing pharmaceutical form Dipyridamole-containing pharmaceutical form

1982-06-17

1984-01-24

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 19, 424 20, 424 21, 424 22, 424 32, 424 35, 424 37, 424 38, 424251, 424267, A61K 900, A61K 920, A61K 948, A61K 31445

Patent

active

044276486

ABSTRACT:
This invention relates to vehicles for the administration of dipyridamole. More specifically, this invention relates to a method of treating cardiovascular disorders in a host in need of such treatment which comprises administering to said host a cardiovascularly effective amount of a composition comprised of (i) dipyridamole or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 5 acid equivalents to 1 mol of dipyridamole, preferably in the form of particles having particle sizes of from about 0.1 to 2.0 mm.

REFERENCES:
patent: 4361546 (1982-11-01), Stricker et al.
patent: 4367217 (1983-01-01), Gruber et al.

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