Dipyricamole sustained release forms comprising lacquer-coated p

Details Dipyricamole sustained release forms comprising lacquer-coated p Dipyricamole sustained release forms comprising lacquer-coated p

1980-12-31

1983-01-04

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 20, 424 21, 424 22, 424 32, 424 33, 424 35, 427 3, A61K 922, A61K 926, A61K 948

Patent

active

043672175

ABSTRACT:
This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating surrounding said spheroid particles, said coating being comprised of from about 50 to 100 percent by weight of acid-insoluble lacquers soluble in intestinal juices and from about 0 to 50 percent by weight of lacquers insoluble in gastric and intestinal juices and said coating being present in an amount of from about 3 to 30 percent by weight, based on the weight of the spheroid particles, and to the preparation of such a composition.

REFERENCES:
patent: 2853420 (1958-09-01), Lowey
patent: 2928770 (1960-03-01), Bardani
patent: 3081233 (1963-03-01), Enz et al.
patent: 3247066 (1966-04-01), Micosovich
patent: 3344029 (1967-09-01), Berger
patent: 3538214 (1970-11-01), Polli et al.
patent: 3775537 (1973-11-01), Lehmann et al.
patent: 3835221 (1974-09-01), Fulberth et al.
patent: 3917813 (1975-11-01), Pedersen
patent: 3954959 (1976-05-01), Pedersen
patent: 4083949 (1978-04-01), Benedickt
patent: 4193985 (1980-03-01), Bechgaard et al.

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