Diphosphonoalkane carboxylic acids, process of preparation and m

Details Diphosphonoalkane carboxylic acids, process of preparation and m Diphosphonoalkane carboxylic acids, process of preparation and m

1977-09-14

1978-10-17

Evans, Joseph E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 49, C07F 938, A61K 716

Patent

active

041208900

ABSTRACT:
Diphosphonoalkane carboxylic acids having the formula ##STR1## wherein R is H or --CH.sub.2 --CH.sub.2 --COOH; as well as their water-soluble salts. The compounds are excellent sequestering agents, especially for alkaline earth and earth metal ions. They are stabilizers for percompounds and are useful in the delaying of the setting times for gypsum. In addition, the compounds are useful in cosmetic preparations, such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and are useful in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficultly soluble calcium salts in the animal body.

REFERENCES:
patent: 3093672 (1963-06-01), Miller
patent: 3404178 (1968-10-01), Roy
Lange, "Handbook of Chemistry," (1961), 10th ed., pp. 460, 461.

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