Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1990-06-13
1991-11-05
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514587, 514596, 514598, 564 28, 564 29, 564 52, 564 53, 564 54, A61K 3117, C07C33518, C07C27534
Patent
active
050632477
ABSTRACT:
Novel diphenylurea derivatives represented by the following formula (I): ##STR1## wherein R.sub.1 is an alkyl group of 5 to 18 carbon atoms, each of R.sub.2 and R.sub.3 is independently an alkyl group of 1 to 5 carbon atoms, an alkoxy group of 1 to 5 carbon atoms or a halogen atom, R.sub.4 is hydrogen atom, an alkyl group of 1 to 5 carbon atoms, an alkoxy group of 1 to 5 carbon atoms or a halogen atom, and X is oxygen atom or sulfur atom, are provided.
The compounds are potent in reducing the cholesterol level in serum, and useful for treating hyperlipemia and atherosclerosis.
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Callender et al., "Anticoccidial Composition and Carbanilides", CA 94, 71498v (1981).
Inoue Shinya
Sekiya Tetsuo
Suzuki Kazuo
Taniguchi Masao
Umezu Kohei
Mitsubishi Kasei Corporation
Raymond Richard L.
Treanor Susan P.
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