Diphenylpyridine derivatives, preparation and therapeutic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S184000, C546S192000, C546S193000, C546S268100, C546S281700, C546S283400, C514S315000

Reexamination Certificate

active

07345059

ABSTRACT:
The invention relates to 5,6-diphenylpyridine-3-carboxamide derivatives of general formula (I):where:R1represents hydrogen or a (C1-C4)alkyl;R2represents:a monoazo saturated heterocycle of 5 to 7 atoms, the nitrogen atom being substituted with a (C1-C4)alkanoyl;NR10R11;a nonaromatic (C3-C10) carbocycle more than tri-substituted with (C1-C4)alkyl;a nonaromatic (C11-C12) carbocycle unsubstituted or mono- or polysubstituted with (C1-C4)alkyl;a monooxygenated saturated heterocycle with 5 to 7 atoms, more than tri-substituted with (C1-C4)alkyl;or R1and R2, together with the nitrogen atom to which the above are bonded, form a 4-disubstituted piperidin-1-yl group;the salts, solvates and hydrates thereof. The invention further relates to a method for production and therapeutic application thereof.

REFERENCES:
patent: 2816938 (2002-05-01), None
patent: WO 97/19063 (1997-05-01), None
patent: WO 03/082191 (2003-10-01), None
patent: WO 03/084930 (2003-10-01), None
patent: WO 03/084943 (2003-10-01), None
Roger G. Pertwee, Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development, Exp. Opin Invest. Drugs (2000, pp. 1553-1571, vol. 9 (7).

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