Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-07-09
2000-04-18
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548237, 548238, 548239, A61K 3142, C07D26310
Patent
active
060515899
DESCRIPTION:
BRIEF SUMMARY
The invention relates to novel diphenyloxazoline derivatives, to a number of processes for their preparation and to their use for combating animal pests.
It is already known that certain oxazoline derivatives possess insecticidal and acaricidal properties (cf. e.g. EP-A 0 345 775 and EP-A 0 432 661). However, the activity of these previously known compounds does not give complete satisfaction in all areas of application, especially at low application rates and concentrations.
The novel diphenyloxazoline derivatives of the formula (I) have now been found ##STR2## in which a) A represents tri- to pentasubstituted phenyl and substituent is not fluorine, chlorine, bromine, C.sub.1 -C.sub.6 -alkyl or C.sub.1 -C.sub.6 -alkoxy.
It has also been found that diphenyloxazoline derivatives of the formula (I) are obtained by ##STR3## in which B is as defined above ##STR4## in which A and B are as defined above ##STR5## in which A and B are as defined above; and arylsulfonyloxy
It has also been found that diphenyloxazoline derivatives of the formula (I) are very highly suited to combating animal pests. They are distinguished in particular by high activity towards arthropods and nematodes.
Surprisingly, the diphenyloxazoline derivatives of the formula (I) according to the invention display a considerably improved activity towards animal pests than the previously known compounds which are closest in terms of constitution.
A general definition of the compounds according to the invention is given by the formula (I). identical or different substituents consisting of halogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.1 -C.sub.6 -halogenoalkyl, C.sub.1 -C.sub.6 -halogenoalkoxy, C.sub.1 -C.sub.6 -halogenoalkylthio, nitro or cyano. identical or different substituents consisting of oxygen atoms, optionally substituted by C.sub.1 -C.sub.4 -alkyl, or C.sub.3 -C.sub.6 -cycloalkyl and/or halogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy, cyclohexyl or phenyl; different substituents consisting of halogen, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -halogenoalkyl; benzylthio or styryl each of which is optionally mono- to trisubstituted by identical or different substituents consisting of C.sub.1 -C.sub.12 -alkyl, halogen, cyano, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -halogenoalkoxy, C.sub.1 -C.sub.6 -alkoxy-C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxyethyleneoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.1 -C.sub.6 -halogenoalkylthio or trimethylsilyl. identical or different substituents consisting of -C.sub.6 -alkylthio, C.sub.1 -C.sub.6 -halogenoalkyl, C.sub.1 -C.sub.6 -halogenoalkoxy, C.sub.1 -C.sub.6 -halogenoalkylthio, nitro or cyano. identical or different substituents consisting of oxygen atoms, -alkyl, or C.sub.3 -C.sub.6 -cycloalkyl and/or halogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -alkoxy, cyclohexyl or phenyl; different substituents consisting of halogen, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -halogenoalkyl; benzylthio or styryl each of which is optionally mono- to trisubstituted by identical or different substituents consisting of C.sub.1 -C.sub.12 -alkyl, halogen, cyano, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -halogenoalkoxy, C.sub.1 -C.sub.6 -alkoxy-C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C6-alkoxyethyleneoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.1 -C.sub.6 -halogenoalkylthio or trimethylsilyl, C.sub.1 -C.sub.6 -alkyl or C.sub.1 -C.sub.6 -alkoxy. pentasubstituted by identical or different substituents consisting of -C.sub.3 -alkylthio, C.sub.1 -C.sub.2 -alkyl which is mono- to penta-substituted by identical or different substituents consisting of F and/or Cl, C.sub.1 -C.sub.4 -alkoxy which is mono- to pentasubstituted by identical or different substituents consisting of F and/or Cl, or SCF.sub.3, SCHF.sub.2, nitro or cyano. pentasubstituted by identical or different substituents consisting of different substituents consisting of F and/or Cl, different substituents consisting of F and/or Cl,
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Erdelen Christoph
Kanellakopulos Johannes
Kleefeld Gerd
Kraatz Udo
Mencke Norbert
Bayer Aktiengesellschaft
Coleman Brenda
Raymond Richard L.
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