Diphenylmethylaminoacetamide derivatives as anti-convulsants

Details Diphenylmethylaminoacetamide derivatives as anti-convulsants Diphenylmethylaminoacetamide derivatives as anti-convulsants

1991-10-11

1994-01-11

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

5142275, 5142375, 514255, 514423, 514618, 544 584, 544162, 544391, 546226, 548540, 564162, 564164, 564165, A61K 31165, C07C23720

Patent

active

052781917

ABSTRACT:
A class of diphenylmethylaminoacetamide derivatives is described having use in treatment of CNS dysfunctions such as epilepsy and convulsive disorders. Compounds of most interest are those of the formula ##STR1## wherein each of X and Y is independently selected from hydrido and halo; and wherein each of R.sup.1, R.sup.2 and R.sup.3 is hydrido; or a pharmaceutically-acceptable salt thereof.

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B. Wysocka-Skrzela, Pol. J. Chem, 56 (10-12), 1573-1576 (1982).
E. C. Taylor et al., J. Am. Chem. Soc, 103, pp. 7743-7752 (1981).

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