Diphenyl ether, diphenyl thioether and diphenyl methane phenol m

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424319, 424324, 424330, 560 9, 560 12, 560 13, 560 17, 560 36, 560 42, 562426, 562430, 562431, 562451, 564162, 564165, 564306, 564348, 562441, A61K 31215, C07C10130, C07C10329, C07C 9116

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043894160

ABSTRACT:
Described are compounds of the formula ##STR1## wherein R is hydrogen, loweralkyl, aminomethyl or halo; R.sub.1 is carboxy, carboxyloweralkyl, aminocarbonyl, hydroxymethyl, anilinomethyl, or aminomethyl; A is oxygen, CH.sub.2, Sulfur or a single bond; X is oxygen, CH.sub.2, sulfur or sulfoxide; and Y is hydrogen, loweralkyl or halo and may be the same or different, and pharmaceutically acceptable salts thereof.
The compounds are effective as diuretic agents.

REFERENCES:
patent: 4106925 (1978-08-01), Rohr et al.
patent: 4156011 (1979-05-01), Lafon et al.

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