Diphenyl disulfide compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514275, 544331, 544332, 544296, 5483107, C07D23154, C07D23902, A61K 31495

Patent

active

056985649

ABSTRACT:
Diphenyl disulfide compounds having an inhibiting activity against the production of Interleukin-1.beta. (IL-1.beta.) or the release of Tumor Necrosis Factor.alpha. (TNF.alpha.), which are useful in the treatment or prophylaxis of the diseases such as chronic rheumatism and sepsis are described.

REFERENCES:
Dusemund J., "Reactions of 1-Aminothioxanthone-6,6-Dioxides with Formamide.", Chem. Abs., vol. 83 (1975), #79178, p. 658.
Berge et al., Wiss. Z (1983), 32, 78-9.
Leopold Horner, et al., Phosphorus and Sulfur and The Related Elements. "Phosphororganische Verbindungen 117.sup.1, Eine Neue Methode Zum Nachweis Der Funktionellen Gruppen: OH, NH.sub.2 Und Sh Durch Auslosung Von Fluoreszenz", 1987, vol. 32, pp. 91-97.

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