Diphenic acid monoamides

Details Diphenic acid monoamides Diphenic acid monoamides

1986-04-02

1988-11-22

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C10172

Patent

active

047867558

ABSTRACT:
The present invention provides various novel diphenic acid monoamide compounds, novel pharmaceutical compositions and methods of use thereof, as well as novel methods of synthesis therefor. The novel diphenic acid monoamides of the present invention are leukotriene antagonists, 5-lipoxygenase inhibitors, and mediator release inhibitors providing activity useful for treating asthma, allergies, cardiovascular diseases, migraines, and immunoinflammatory conditions.

REFERENCES:
patent: 3995045 (1976-11-01), Wade et al.
patent: 4602023 (1986-07-01), Kiely et al.
Pan et al., "Jou. of Med. Chem.," vol. 13, No. 3, (1970) pp. 567-568.

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