Dipeptidyl peptidases

Details Dipeptidyl peptidases Dipeptidyl peptidases

2005-04-19

2005-04-19

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

Reexamination Certificate

active

06881564

ABSTRACT:
The present invention provides an isolated peptide that comprises the sequence shown in SEQ ID NO:1 or a sequence which has at least 95% identity with SEQ ID NO:1, and which has the same substrate specificity as SEQ ID NO:1. Preferred peptides include peptides having the amino acid sequences set forth in SEQ ID NO: 3, 5, and 7. The isolated peptide is useful as a dipeptidyl aminopeptidase.

REFERENCES:
patent: 4977085 (1990-12-01), Sprague et al.
Qi et al Human DPPIV related serine protease DPRP-1. from WO200231134 Apr.-18-2002. SeqABG61591. Alignment with SEQ ID No.: 1.*
Kawakami et al EMBL Acc#AK000290 alignment with SEQ ID No.:1 Feb. 22, 2000.*
Database EMBL'Online! retrieved from EMBL Database accession No. AA417787; XP002266787 (Abstract).
Database EMBL'Online! retrieved from EMBL Database accession No. AA278625; XP002266788 (Abstract).
Database EMBL'Online! retrieved from EMBL Database accession No. AA496257; XP002266789 (Abstract).

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