Dipeptide production method, L-amino acid amide hydrolase...

Details Dipeptide production method, L-amino acid amide hydrolase... Dipeptide production method, L-amino acid amide hydrolase...

2006-05-02

2006-05-02

Patterson, Jr., Charles L. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

C435S223000

Reexamination Certificate

active

07037673

ABSTRACT:
A process for industrially advantageously producing a dipeptide via a convenient pathway starting with less expensive and easily available materials is provided. A dipeptide is produced from an L-amino acid amide and an L-amino acid by using a culture of a microbe capable of synthesizing the dipeptide from the L-amino acid amide and the L-amino acid, microbial cells separated from the culture or a treated microbial cell product from the microbe. An L-amino acid amide hydrolase is obtained from a microbe belonging to the genuserwinia, genusRhodococcus, genusChryseobacterium, genusMicrococcus, genusCryptococcus, genusTrichosporion, genusRhodosporidium, genusSporobolomyces, genusTremela, genusTorulaspora, genusSterigmatomycesor genusRhodotorula. The hydrolase catalyzes a reaction that produces a dipeptide from an L-amino acid amide and an L-amino acid.

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