Dipeptide derivatives, process for manufacture and pharmaceutica

Details Dipeptide derivatives, process for manufacture and pharmaceutica Dipeptide derivatives, process for manufacture and pharmaceutica

1975-10-16

1977-08-30

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125TR, 2601125R, A61K 3700, C07C10352

Patent

active

040455564

ABSTRACT:
Dipeptide compounds derived from histidyl-proline, namely acyl derivatives of histidyl prolinamide such as orotyl-L-histidyl-L-prolinamide, L-2-oxo-imidazolidine-4-carbonyl-L-histidyl-L-prolinamide, L-50-oxo-thiomorpholine-3-carbonyl-L-histidyl-L-prolinamide and others (and salts of such compounds with pharmaceutically acceptable acids) useful as psycho-stimulating or anti-depressive agents, respectively.
Also a process of preparation.

REFERENCES:
patent: 3912705 (1975-10-01), Fujino et al.
J. D. Roberts and M. C. Caserio, "Basic Principles of Organic Chemistry", Benjamin, Inc., New York, 1965, p. 664.

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