Dipeptide derivatives

Details Dipeptide derivatives Dipeptide derivatives

1992-11-10

1993-06-29

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544158, 544168, C07K 506

Patent

active

052236153

ABSTRACT:
A dipeptide derivative of the formula (I) is provided, which is capable of inhibiting the enzymatic activity of renin and thereby depressing the renin-angiotensin system and lowering the blood pressure, provided. ##STR1## wherein: R.sup.1 is C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.3 -C.sub.10 cycloalkyl, aryl, or heterocyclic radical;

REFERENCES:
patent: 4791102 (1988-12-01), Bernat et al.
patent: 5089616 (1992-02-01), Belmont et al.

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