Dipeptide derivatives

Details Dipeptide derivatives Dipeptide derivatives

1992-11-10

1993-12-21

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544238, 544335, 544406, 546146, 546168, 546209, 546275, 548200, 548214, 548215, 548253, 548255, 5482668, C07D40106, C07D41306, C07D27718, C07D24914

Patent

active

052722686

ABSTRACT:
A following dipeptide derivative of the following formula (I) is provided, which is capable of inhibiting the enzymatic activity of renin and thereby depressing the renin-angiotensin system and lowering the blood pressure. ##STR1## wherein: R.sup.1 is C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.3 -C.sub.10 cycloalkyl, aryl, or heterocyclic radical;

REFERENCES:
patent: 4791102 (1988-12-01), Bernat et al.

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