Dipeptide derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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544238, 544335, 544406, 546146, 546168, 546209, 546275, 548200, 548214, 548215, 548253, 548255, 5482668, C07D40106, C07D41306, C07D27718, C07D24914

Patent

active

052722686

ABSTRACT:
A following dipeptide derivative of the following formula (I) is provided, which is capable of inhibiting the enzymatic activity of renin and thereby depressing the renin-angiotensin system and lowering the blood pressure. ##STR1## wherein: R.sup.1 is C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.3 -C.sub.10 cycloalkyl, aryl, or heterocyclic radical;

REFERENCES:
patent: 4791102 (1988-12-01), Bernat et al.

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