Dioxolanic amine with pharmacological activity, its method of pr

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

549448, 514465, A61K 3134, C07D31700

Patent

active

044951990

ABSTRACT:
A new dioxolanic amine is disclosed, with pharmacological activity of the following structural formula I: ##STR1## as well as its pharmaceutically acceptable salts, possessing intense vasodilatory, anti-angina and anti-arrhythmic activity, accompanied by a low toxicity; its method of preparation; pharmaceutical compositions containing the said compounds; and the treatment and prevention various pathological conditions with the use of said compositions. Also disclosed are new dioxolanic compound of the following structural formula II: ##STR2## which is an intermediate compound in the preparation of the formula I compound; and its method of preparation.

REFERENCES:
patent: 3972900 (1976-08-01), Fothergill et al.
patent: 4237144 (1980-12-01), Cragoe, Jr. et al.

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