Dioxin analogues and methods and kits for searching out...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C435S004000, C435S007310, C435S007320, C435S029000

Reexamination Certificate

active

10472382

ABSTRACT:
The present invention provides a novel dioxin analogue for use in the search for organisms capable of degrading dioxin. The dioxin analogue is represented by the following chemical formula (1) or (2):

REFERENCES:
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Webster's II New Riverside Dictionary (1994) (Houghton-Mifflin Company: Boston, MA) p. 667.
Richard C. Cambie et al., “Syntheses of dibenzo [b, e][1,4] dioxinderivatives via iron complexes, and further functionalizations via directed metallation”, Journal of Organometallic Chemistry, 420, 1991, pp. 287-418.
Ronald G. Sutherland et al., “Synthesis of some heterocyclic skeletons via organoiron complexes. Crystal and molecular structure of (5a, 6, 7, 8, 9, 9a-eta. 6-1, 4-benzoxathiino [3, 2-b] pyrdiine) (.eta.5-cyclopentadienyl)iron hexafluorophosphate”, J. Heterocycl. Chem., 25, 1911, 1998.
M.A. Denomme et al., “Effects of substituents on the cytosolic receptor-binding avidities and aryl hydrocarbon hydroxylase induction potencies of 7-substituted 2,3-dichlorodibenzo-p-dioxins. A quantitative structure-activity relationship analysis”, Molecular Pharmacology, 27, pp. 656-661, 1985.
Rebecca D. Prokipcak et al., “7-substituted-2,3-dichlorodibenzo-p-dioxins as competitive ligands for the Ah receptor: quantitative structure-activity relationships (QSARs) and a comparison of human receptor with Ah receptor from rodents”, Chemosphere, vol. 20, Nos. 7-9, pp. 1221-1228, 1990.

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