Dioxaphosphorinanes, their preparation and use for resolving opt

Details Dioxaphosphorinanes, their preparation and use for resolving opt Dioxaphosphorinanes, their preparation and use for resolving opt

1987-06-19

1989-03-21

Sutto, Anton H.

Glass manufacturing

562401, 564303, 564304, C07F 921, C07B 5700

Patent

active

048144770

ABSTRACT:
A new family of compounds known as dioxaphosphorinanes having the formula: ##STR1## wherein, M represents a hydrogen atom, a metal ion or an ammonium ion; R1 and R2, individually, represents a hydrogen atom, a halogen atom, an alkyl group having from 1 to 4 carbon atoms, an alkoxy group having from 1 to 4 carbon atoms or a nitro group or, together, represent a methylene dioxy group; and R3 and R4, individually, represents a halogen atom, an alkyl group having from 1 to 4 carbon atoms or a hydrogen atom so long as only one of the groups R3 and R4 represents a hydrogen atom or, together, represent a cyclohexyl group.
A method for preparing these dioxaphosphorinanes by reacting phosphoryl chloride with a substituted 1-phenyl-1,3-dihydroxypropane is described. Also described is a method for resolving the new dioxaphosphorinanes into their optical isomers by reacting them with an optically active amino-compound. Similarly, a method for resolving the racemates of several amino-compounds, such as hydroxyphenylglycine and phenylalanine, into optically active isomers by reacting with a dioxaphosphorinane is described.

REFERENCES:
Kainosho et al., "Bull. of the Chemical Society of Japan," vol. 42, (1969) pp. 1713-1717.
Matrosov et al., "Chem. Abst.", vol. 85, (1976) 85:20188a.
Cram et al., "Organic Chemistry," (1964) Second Editions, pp. 162-175.
Majoral et al., "Chem Abst.," vol. 69,(1968) 26898y.

Affiliated with

Also associated with

Rating

Dioxaphosphorinanes, their preparation and use for resolving opt does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dioxaphosphorinanes, their preparation and use for resolving opt, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dioxaphosphorinanes, their preparation and use for resolving opt will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-478091